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Proceedings Paper

Quasi-elastic light scattering spectroscopy of single biological cells under a microscope
Author(s): Toyoichi Tanaka; Izumi Nishio; Joyce Peetermans; Sridhar Gorti
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Paper Abstract

A microscope laser light scattering setup has been developed that allows to carry out the intensity autocorrelation spectroscopy of the light scattered from a volume as small as (2 . tm)3. This noninvasive technique makes cytoplasmic studies possible inside single live biological cells. The technique has been proven powerful as revealed in the studies of hemoglobin aggregation within sickle red blood cells crystallin synthesis in the lens fiber cells and secretion of protein containing granules in the acinar cells. 1.

Paper Details

Date Published: 1 May 1991
PDF: 8 pages
Proc. SPIE 1403, Laser Applications in Life Sciences, (1 May 1991); doi: 10.1117/12.57326
Show Author Affiliations
Toyoichi Tanaka, Massachusetts Institute of Technology (United States)
Izumi Nishio, Massachusetts Institute of Technology (United States)
Joyce Peetermans, Massachusetts Institute of Technology (United States)
Sridhar Gorti, Massachusetts Institute of Technology (United States)

Published in SPIE Proceedings Vol. 1403:
Laser Applications in Life Sciences
Sergei A. Akhmanov; Marina Yu. Poroshina, Editor(s)

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