Share Email Print

Proceedings Paper

Optimization of illumination for a diffuse-spectroscopy-based early melanoma diagnostic imager
Author(s): Andrew H. Rawicz; Ivan Melnyk; Bradley Oldham
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

An optical system injecting light directly to skin and collecting spectrally modified within skin backscattered portion of light has been designed and fabricated. This method reduces the noise generated by specular component nearly to zero. Seven clinical tests performed on patients with suspect skin lesions have been tested with our device and later biopsy was taken as a “gold standard” procedure. Three cases proved to be melanoma and our spectra indicated differences from those collected from non-melanoma lesions. The process of collecting spectral data was too time consuming. To accelerate the process of data collection from the skin, using the same principle of diffuse spectroscopy, an imaging device was conceived which is able to collect skin spectral response at once from a relatively sizeable skin area. The requirement of a negligible specular component was considered of paramount importance. Two approaches can satisfy this requirement: 1. Collection of backscattered light directly from the skin 2. Injection of illuminating light directly to the skin without creating reflections directly from the skin. We decided to use the second approach and construct a circular, circumferential illuminator with angled light injection. Before fabricating this illuminator, a thorough analysis was performed to optimize its radius and angle of injection in order to receive the highest uniformity of diffuse light in the skin. Monte-Carlo simulation was applied to a three layer skin approximation.The results of the simulation will be presented.

Paper Details

Date Published: 9 December 2004
PDF: 8 pages
Proc. SPIE 5578, Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education, (9 December 2004); doi: 10.1117/12.566973
Show Author Affiliations
Andrew H. Rawicz, Simon Fraser Univ. (Canada)
Ivan Melnyk, Photon Control Systems (Canada)
Bradley Oldham, Simon Fraser Univ. (Canada)

Published in SPIE Proceedings Vol. 5578:
Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education
Marc Nantel; Glen Herriot; Graham H. McKinnon; Leonard MacEachern; Robert A. Weersink; Rejean Munger; Andrew Ridsdale, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?