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Proceedings Paper

Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine
Author(s): I. G. Meerovich; Irina Yu. Kubasova; Gennadii A. Meerovich; Alexander A. Stratonnikov; S. A. Demura; Alexandr S. Brandis; V. Rosenbach-Belkin; Avigdor Scherz
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Paper Abstract

The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

Paper Details

Date Published: 21 June 2004
PDF: 10 pages
Proc. SPIE 5449, Eighth International Conference on Laser and Laser Information Technologies, (21 June 2004); doi: 10.1117/12.563144
Show Author Affiliations
I. G. Meerovich, N.N. Blokhin Memorial Cancer Research Ctr. (Russia)
Irina Yu. Kubasova, N.N. Blokhin Memorial Cancer Research Ctr. (Russia)
Gennadii A. Meerovich, A.M. Prokhorov General Physics Institute (Russia)
Alexander A. Stratonnikov, A.M. Prokhorov General Physics Institute (Russia)
S. A. Demura, I.M. Sechenov Moscow Medical Academy (Russia)
Alexandr S. Brandis, Weizmann Institute of Science (Israel)
V. Rosenbach-Belkin, Weizmann Institute of Science (Israel)
Avigdor Scherz, Weizmann Institute of Science (Israel)


Published in SPIE Proceedings Vol. 5449:
Eighth International Conference on Laser and Laser Information Technologies
Vladislav Ya. Panchenko; Nikola V. Sabotinov, Editor(s)

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