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Proceedings Paper

Artificial muscle valves for responsive drug delivery systems
Author(s): Chong Wang; Han Xu; ChunLei Wang; Jim V. Zoval; Marc J. Madou
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Paper Abstract

A controlled drug delivery system in which drug release is achieved by actuating an array of polymeric valves on a set of drug reservoirs is introduced. The valves are bilayer structures with one layer, a thin film of evaporated gold and the other, electrochemically deposited polypyrrole, which is also called “artificial muscle”. The valves are made in the shape of flaps fixed on one side to the valve seats. Drug reservoirs are covered by an array of such valves. Release of the drugs stored in the reservoirs is accomplished by bending the bilayer flaps back with a small applied bias. The fabrication procedures and proof-of-principle drug release experiments for this controlled drug delivery device are described. Energy consumption of this reversible valve design is compared with metal corrosion based valves developed earlier by other groups and our group.

Paper Details

Date Published: 16 August 2004
PDF: 7 pages
Proc. SPIE 5455, MEMS, MOEMS, and Micromachining, (16 August 2004); doi: 10.1117/12.548756
Show Author Affiliations
Chong Wang, Univ. of California/Irvine (United States)
Han Xu, Univ. of California/Irvine (United States)
ChunLei Wang, Univ. of California/Irvine (United States)
Jim V. Zoval, Univ. of California/Irvine (United States)
Marc J. Madou, Univ. of California/Irvine (United States)

Published in SPIE Proceedings Vol. 5455:
MEMS, MOEMS, and Micromachining
Hakan Urey; Ayman El-Fatatry, Editor(s)

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