The purpose of this paper is to demonstrate the use of some methods of signal analysis, performed on ECG and in some cases blood pressure signals, for the classification of the health status of the heart of mice and rats. Spectral and wavelet analysis were performed on the raw signals. FFT-based coherence and phase was also calculated between blood pressure and raw ECG signals. Finally, RR-intervals were deduced from the ECG signals and an analysis of the fractal dimensions was performed. The analysis was made on data from mice and rats. A correlation was found between the health status of the mice and the rats and some of the statistical descriptors, most notably the phase of the cross-spectra between ECG and blood pressure, and the fractal properties and dimensions of the interbeat series (RR-interval fluctuations).

Date Published: 25 May 2004
PDF: 9 pages
Proc. SPIE 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II, (25 May 2004); doi: 10.1117/12.546908

Published in SPIE Proceedings Vol. 5467:
Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II
Derek Abbott; Sergey M. Bezrukov; Andras Der; Angel Sanchez, Editor(s)