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Proceedings Paper

Detection of esophageal cancer by human serum using autofluorescence and Raman spectroscopy
Author(s): Xiaozhou Li; Chunde Jia; Huiqiang Jin; Rong Wang
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Paper Abstract

We detected the serum of patient's and normal using auto-fluorescence and Raman spectroscopy. The serum spectrum was excited by laser of the wavelength 488.0 nm and 514.5 nm. Compared with the normal serum, we can observe the apparent differences of autofluorescence-Raman spectroscopy: the majority of the fluorescence spectrum did not have violent alteration, but three Raman peak had disappeared or very weak. After operation, the Raman spectrum of patient's serum is similar to the normal. And fluorescence peak's red shift, α-value also provide the reference for future research. We assume that following the progression of the tumor, β-value will decrease following the aggravation of cancer. The result of spectrum analysis is accordance with the clinical diagnosis.

Paper Details

Date Published: 4 December 2003
PDF: 6 pages
Proc. SPIE 5255, Biomolecular Photonics and Multidimensional Microscopy, (4 December 2003); doi: 10.1117/12.546247
Show Author Affiliations
Xiaozhou Li, Dalian Univ. of Technology (China)
Shenyang Institute of Technology (China)
Chunde Jia, Shenyang Institute of Technology (China)
Huiqiang Jin, Shenyang Institute of Technology (China)
Rong Wang, Liaoning Univ. (China)

Published in SPIE Proceedings Vol. 5255:
Biomolecular Photonics and Multidimensional Microscopy
Qingming Luo; Min Gu, Editor(s)

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