Share Email Print

Proceedings Paper

Chalcogenide glass fibers used for in situ infrared spectroscopy in biology and medicine
Author(s): Julie Keirsse; Bruno Bureau; Catherine Boussard-Pledel; P. Leroyer; M. Ropert; Virginie Dupont; Marie Laure Anne; C. Ribault; Olivier Sire; Olivier Loreal; Jean Luc Adam
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Chalcogenide glass optical fibers possess very low optical losses in the middle infrared range from 2 to 12 mm. They were used to implement remote infrared spectroscopy, known as Fiber Evanescent Wave Spectroscopy (FEWS). Due to their hydrophobic behavior, such sensor is especially suitable for application in biology and medicine where water is a nuisance to detect relevant information. Moreover, the design of the sensor using tapered fibers enables to improve the signal to noise ratio. Then, once coupled with unsupervised analysis technique such as Principle Component Analysis (PCA), it has been shown that this tool is efficient to differentiate between obese and control mice by recording their serum FEWS spectra. The same method has been carried out to detect in situ the both phenotypes of a bacterial culture.

Paper Details

Date Published: 1 September 2004
PDF: 8 pages
Proc. SPIE 5459, Optical Sensing, (1 September 2004); doi: 10.1117/12.545430
Show Author Affiliations
Julie Keirsse, Univ. de Rennes 1 (France)
Bruno Bureau, Univ. de Rennes 1 (France)
Catherine Boussard-Pledel, Univ. de Rennes 1 (France)
P. Leroyer, INSERM (France)
M. Ropert, CHRU Pontchaillou (France)
Virginie Dupont, Univ. de Bretagne-Sud (France)
Marie Laure Anne, Univ. de Rennes 1 (France)
C. Ribault, INSERM (France)
Olivier Sire, Univ. de Bretagne-Sud (France)
Olivier Loreal, INSERM (France)
Jean Luc Adam, Univ. de Rennes 1 (France)

Published in SPIE Proceedings Vol. 5459:
Optical Sensing
Brian Culshaw; Anna Grazia Mignani; Rainer Riesenberg, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?