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Proceedings Paper

Creating the invisible man
Author(s): A. J. Welch; Chris Humphrey; Gracie Vargas; Oliver F. Stumpp; Chris G. Rylander
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Paper Abstract

Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm2] required to coagulate dermal blood vessels.

Paper Details

Date Published: 1 July 2004
PDF: 6 pages
Proc. SPIE 5319, Laser Interaction with Tissue and Cells XV, (1 July 2004); doi: 10.1117/12.537256
Show Author Affiliations
A. J. Welch, Univ. of Texas/Austin (United States)
Chris Humphrey, Univ. of Texas/Austin (United States)
Gracie Vargas, Univ. of Texas Medical Branch (United States)
Oliver F. Stumpp, Univ. of Texas/Austin (United States)
Chris G. Rylander, Univ. of Texas/Austin (United States)

Published in SPIE Proceedings Vol. 5319:
Laser Interaction with Tissue and Cells XV
Steven L. Jacques; William P. Roach, Editor(s)

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