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Proceedings Paper

Quantification of cross-sectional artery wall motion with IVUS image registration
Author(s): Kevin D. Oakeson; Hui Zhu; Morton H. Friedman
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Paper Abstract

Atherosclerotic lesions have been shown to have different mechanical properties than the non-diseased artery. Calculating vessel wall strain from cross-sectional vessel wall motions allows for the measurement of local stiffness. In this paper, a robust method is developed to track cross-sectional displacements of an artery wall using two different intravascular ultrasound (IVUS) images acquired at two different pressure levels respectively. First, the vessel wall region in one image is segmented semi-automatically by refining two spline-based contours to the locations of inner and outer vessel wall borders. Then the ringlike wall region in one image is registered to its counterpart in the other image in polar coordinates. The registration is performed by minimizing an energy function of the 2D motion field based on a spline-deformable-model. Both intensity and gradient information of the images are used to construct the energy function so that an accurate registration can be achieved. Registration accuracy was tested on simulated motions using IVUS images of a human coronary artery and a porcine carotid. The wall displacement fields calculated from real motion images are also demonstrated.

Paper Details

Date Published: 28 April 2004
PDF: 12 pages
Proc. SPIE 5373, Medical Imaging 2004: Ultrasonic Imaging and Signal Processing, (28 April 2004); doi: 10.1117/12.536523
Show Author Affiliations
Kevin D. Oakeson, Duke Univ. (United States)
Hui Zhu, Duke Univ. (United States)
Morton H. Friedman, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 5373:
Medical Imaging 2004: Ultrasonic Imaging and Signal Processing
William F. Walker; Stanislav Y. Emelianov, Editor(s)

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