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Proceedings Paper

Computer-aided detection of lung cancer on chest radiographs: effect of machine CAD true positive/false negative detections on radiologists' confidence level
Author(s): Matthew T. Freedman M.D.; Teresa Osicka; Shih-Chung Benedict Lo; Fleming Lure; Xin-Wei Xu; Jesse Lin; Hui Zhao; Ron Zhang
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Paper Abstract

This paper evaluates the effect of Computer-Aided Detection prompts on the confidence and detection of cancer on chest radiographs. Expected findings included an increase in confidence rating and a decrease in variance in confidence when radiologists interacted with a computer prompt that confirmed their initial decision or induced them to switch from an incorrect to a correct decision. Their confidence rating decreased and the variance of confidence rating increased when the computer failed to confirm a correct or incorrect decision. A population of cases was identified that changed among reading modalities. This unstable group of cases differed between the Independent and Sequential without CAD modalities in cancer detection by radiologists and cancer detection by machine. CAD prompts induced the radiologists to make two types of changes in cases: changes on the sequential modality with CAD that restored an initial diagnosis made in the Independent read and new changes that were not present in the Independent or Sequential reads without CAD. This has implications for double reading of cases. The effects of intra-observer variability and inter-observer variability are suggested as potential causes for differences in statistical significance of the Independent and Sequential Design approaches to ROC studies.

Paper Details

Date Published: 4 May 2004
PDF: 7 pages
Proc. SPIE 5372, Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment, (4 May 2004); doi: 10.1117/12.536157
Show Author Affiliations
Matthew T. Freedman M.D., ISIS/Georgetown Univ. Medical Ctr. (United States)
Deus Technologies Inc. (United States)
Teresa Osicka, ISIS/Georgetown Univ. (United States)
Shih-Chung Benedict Lo, ISIS/Georgetown Univ. (United States)
Fleming Lure, Deus Technologies (United States)
Xin-Wei Xu, Deus Technologies (United States)
Jesse Lin, Deus Technologies (United States)
Hui Zhao, Deus Technologies (United States)
Ron Zhang, Deus Technologies (United States)

Published in SPIE Proceedings Vol. 5372:
Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment
Dev P. Chakraborty; Miguel P. Eckstein, Editor(s)

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