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Proceedings Paper

Fast approach to evaluate MAP reconstruction for lesion detection and localization
Author(s): Jinyi Qi; Ronald H. Huesman
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Paper Abstract

Lesion detection is an important task in emission tomography. Localization ROC (LROC) studies are often used to analyze the lesion detection and localization performance. Most researchers rely on Monte Carlo reconstruction samples to obtain LROC curves, which can be very time-consuming for iterative algorithms. In this paper we develop a fast approach to obtain LROC curves that does not require Monte Carlo reconstructions. We use a channelized Hotelling observer model to search for lesions, and the results can be easily extended to other numerical observers. We theoretically analyzed the mean and covariance of the observer output. Assuming the observer outputs are multivariate Gaussian random variables, an LROC curve can be directly generated by integrating the conditional probability density functions. The high-dimensional integrals are calculated using a Monte Carlo method. The proposed approach is very fast because no iterative reconstruction is involved. Computer simulations show that the results of the proposed method match well with those obtained using the tradition LROC analysis.

Paper Details

Date Published: 4 May 2004
PDF: 10 pages
Proc. SPIE 5372, Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment, (4 May 2004); doi: 10.1117/12.535916
Show Author Affiliations
Jinyi Qi, Lawrence Berkeley National Lab. (United States)
Ronald H. Huesman, Lawrence Berkeley National Lab. (United States)

Published in SPIE Proceedings Vol. 5372:
Medical Imaging 2004: Image Perception, Observer Performance, and Technology Assessment
Dev P. Chakraborty; Miguel P. Eckstein, Editor(s)

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