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Proceedings Paper

Urinary stone composition analysis by coherent scatter: Is a monoenergetic source necessary?
Author(s): Melanie T. M. Davidson; Deidre Louise Batchelar; Sujeevan Velupillai; Ian A. Cunningham
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Paper Abstract

Urinary stone components can be characterized through their diffraction signatures using monoenergetic or polyenergetic x rays. Sharp characteristic diffraction peaks are observed under monoenergetic conditions, facilitating component separability in measurements of stones with mixed composition. This favors uniqueness of a materials analysis solution. However, these monoenergetic techniques are either impractical (as with synchrotron radiation) or impossible to perform in situ (as with conventional low energy diffractometry). Alternatively, our approach measures signals from x-ray diffraction, or coherent scatter (CS), for stones and their components using polyenergetic x rays from diagnostic equipment, allowing for in situ applications. Although the polyenergetic x-ray spectrum is the primary contributor to the angular broadening of diffraction peaks in our measured CS cross-sections, we show that it is possible to relate the polyenergetic and monoenergetic results through a “non-stationary” convolution operation. This requires the computation of a linear superposition integral of the monoenergetic cross-section with a function representative of the polyenergetic spectrum. Experimentally acquired diffractometry cross-sections of the seven major urinary stone components were subjected to this operation, revealing good agreement of diffraction features with CS. These results indicate that angular resolution is principally hindered by the energy spectrum in CS measurements. Nevertheless, distinct scatter patterns were observed using CS, suggesting that a strictly monoenergetic beam is not required for the depiction of pure stone components.

Paper Details

Date Published: 6 May 2004
PDF: 12 pages
Proc. SPIE 5368, Medical Imaging 2004: Physics of Medical Imaging, (6 May 2004); doi: 10.1117/12.535837
Show Author Affiliations
Melanie T. M. Davidson, Robarts Research Institute (Canada)
Univ. of Western Ontario (Canada)
Deidre Louise Batchelar, Robarts Research Institute (Canada)
Univ. of Western Ontario (Canada)
Sujeevan Velupillai, Robarts Research Institute (Canada)
Univ. of Western Ontario (Canada)
Ian A. Cunningham, Robarts Research Institute (Canada)
Univ. of Western Ontario (Canada)

Published in SPIE Proceedings Vol. 5368:
Medical Imaging 2004: Physics of Medical Imaging
Martin J. Yaffe; Michael J. Flynn, Editor(s)

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