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Proceedings Paper

Effect of projective viewpoint in detecting temporal density changes
Author(s): Jakob Raundahl; Mads Nielsen; Ole Fogh Olsen; Yu Zhao Bagger
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Paper Abstract

An important question in mammographic image analysis is the importance of the projected view of the breast. Can temporal changes in density be detected equally well using either one of the commonly available views Medio-Lateral (ML) and Cranio-Caudal (CC) or a combination of the two? Two sets of mammograms of 50 patients in a double-blind, placebo controlled hormone replacement therapy (HRT) experiment were used. One set of ML and CC view from 1999 and one from 2001. HRT increases density which means that the degree of separation of the populations (one group receiving HRT and the other placebo) can be used as a measure of how much density change information is carried in a particular view or combination of views. Earlier results have shown a high correlation between CC and ML views leading to the conclusion that only one of them is needed for density assessment purposes. A similar high correlation coefficient was observed in this study (0.85), while the correlation between changes was a bit lower (0.71). Using both views to separate the patients receiving hormones from the ones receiving placebo increased the area under corresponding ROC curves from 0.76 ± 0.04 to 0.79 ± 0.04.

Paper Details

Date Published: 12 May 2004
PDF: 8 pages
Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); doi: 10.1117/12.535319
Show Author Affiliations
Jakob Raundahl, IT Univ. Copenhagen (Denmark)
Mads Nielsen, IT Univ. Copenhagen (Denmark)
Ole Fogh Olsen, IT Univ. Copenhagen (Denmark)
Yu Zhao Bagger, Ctr. for Clinical and Basic Research (Denmark)

Published in SPIE Proceedings Vol. 5370:
Medical Imaging 2004: Image Processing
J. Michael Fitzpatrick; Milan Sonka, Editor(s)

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