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Proceedings Paper

Digital tomosynthesis mammography using a parallel maximum-likelihood reconstruction method
Author(s): Tao Wu; Juemin Zhang; Richard Moore; Elizabeth Rafferty; Daniel Kopans; Waleed Meleis; David Kaeli
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Paper Abstract

A parallel reconstruction method, based on an iterative maximum likelihood (ML) algorithm, is developed to provide fast reconstruction for digital tomosynthesis mammography. Tomosynthesis mammography acquires 11 low-dose projections of a breast by moving an x-ray tube over a 50° angular range. In parallel reconstruction, each projection is divided into multiple segments along the chest-to-nipple direction. Using the 11 projections, segments located at the same distance from the chest wall are combined to compute a partial reconstruction of the total breast volume. The shape of the partial reconstruction forms a thin slab, angled toward the x-ray source at a projection angle 0°. The reconstruction of the total breast volume is obtained by merging the partial reconstructions. The overlap region between neighboring partial reconstructions and neighboring projection segments is utilized to compensate for the incomplete data at the boundary locations present in the partial reconstructions. A serial execution of the reconstruction is compared to a parallel implementation, using clinical data. The serial code was run on a PC with a single PentiumIV 2.2GHz CPU. The parallel implementation was developed using MPI and run on a 64-node Linux cluster using 800MHz Itanium CPUs. The serial reconstruction for a medium-sized breast (5cm thickness, 11cm chest-to-nipple distance) takes 115 minutes, while a parallel implementation takes only 3.5 minutes. The reconstruction time for a larger breast using a serial implementation takes 187 minutes, while a parallel implementation takes 6.5 minutes. No significant differences were observed between the reconstructions produced by the serial and parallel implementations.

Paper Details

Date Published: 6 May 2004
PDF: 11 pages
Proc. SPIE 5368, Medical Imaging 2004: Physics of Medical Imaging, (6 May 2004); doi: 10.1117/12.534446
Show Author Affiliations
Tao Wu, Massachusetts General Hospital (United States)
Juemin Zhang, Northeastern Univ. (United States)
Richard Moore, Massachusetts General Hospital (United States)
Elizabeth Rafferty, Massachusetts General Hospital (United States)
Daniel Kopans, Massachusetts General Hospital (United States)
Waleed Meleis, Northeastern Univ. (United States)
David Kaeli, Northeastern Univ. (United States)

Published in SPIE Proceedings Vol. 5368:
Medical Imaging 2004: Physics of Medical Imaging
Martin J. Yaffe; Michael J. Flynn, Editor(s)

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