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Proceedings Paper

Optical coherence tomography in diagnostics and guided surgery of bladder cancer
Author(s): Elena Zagaynova; Olga Streltzova; Natalia D. Gladkova; Natalia M. Shakhova; Felix I. Feldchtein; Vladislav A. Kamensky; Grigory V. Gelikonov; Ekaterina Donchenko
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Paper Abstract

We performed blind recognition of optical coherence tomography (OCT) images of human urinary bladder for diagnostics of carcinoma and premalignant conditions. OCT images of 63 patients were acquired in vivo during cystoscopic examination. The malignant/premalignant conditions were differentiated from benign/reactive with 98% sensitivity and 72% specificity. OCT was also used for intraoperative monitoring of zones around the tumor for adequate resection (31 patients). OCT - guided planning of the resection margin and examination of the postoperative resection line after transurethral resection (TUR) was performed.

Paper Details

Date Published: 1 July 2004
PDF: 10 pages
Proc. SPIE 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII, (1 July 2004); doi: 10.1117/12.530794
Show Author Affiliations
Elena Zagaynova, Nizhny Novgorod Medical Academy (Russia)
Olga Streltzova, Nizhny Novgorod Regional Hospital (Russia)
Natalia D. Gladkova, Nizhny Novgorod Medical Academy (Russia)
Natalia M. Shakhova, Institute of Applied Physics (Russia)
Felix I. Feldchtein, Institute of Applied Physics (Russia)
Imalux Corp. (United States)
Vladislav A. Kamensky, Institute of Applied Physics (Russia)
Grigory V. Gelikonov, Institute of Applied Physics (Russia)
Ekaterina Donchenko, Nizhny Novgorod Research Institute for Trauma and Orthopedics (Russia)

Published in SPIE Proceedings Vol. 5316:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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