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Proceedings Paper

Integrated optical glucose sensor fabricated using PDMS waveguides on a PDMS substrate
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Paper Abstract

This paper describes the design and fabrication of an integrated optical glucose sensing system using the combination of the oxygen sensitive dye tris(2,2’-bipyridyl) dichlororuthenium(II) hexahydrate and glucose oxidase. Layer-by-layer self-assembly is used to immobilize the dye/enzyme system onto the surface of the waveguides. Changes in the enzyme/dye system as it interacts with the surrounding environment are monitored using end-face interaction with light injected into waveguides. The waveguides are thermally-defined monolithic polydimethlysiloxane (PDMS) waveguide system, fabricated on a PDMS substrate. The method of waveguide fabrication is a radical departure from conventional microscale waveguide systems, and offers unique opportunities for integration of this sensor into existing microfluidic systems.

Paper Details

Date Published: 23 December 2003
PDF: 10 pages
Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003); doi: 10.1117/12.530062
Show Author Affiliations
David A. Chang-Yen, Univ. of Utah (United States)
Bruce K. Gale, Univ. of Utah (United States)

Published in SPIE Proceedings Vol. 5345:
Microfluidics, BioMEMS, and Medical Microsystems II
Peter Woias; Ian Papautsky, Editor(s)

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