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Proceedings Paper

Glucose micro- and nano-sensors based on nanoassembled enzyme/polymer/dye composites
Author(s): J. Quincy Brown; Suruchi Chopra; Patrick S. Grant; Michael J. McShane
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Paper Abstract

Minimally-invasive glucose sensors are attractive for disease management as well as medical and biological research applications. Fluorescent sensors, coupling enzymes to catalyze specific reactions with glucose, have been developed for this purpose. Our work has focused on the downscaling of these technologies to the micro- and nano-scale by using self-assembly to build the sensing components of the assays. Both "solid" polymers and hollow microshells have been developed to physically couple the sensing materials together in biocompatible, semipermeable packages suitable for use in biological systems. Fabrication details and sensor characterization are used to demonstrate the potential of these sensor concepts.

Paper Details

Date Published: 18 June 2004
PDF: 10 pages
Proc. SPIE 5325, Optical Diagnostics and Sensing IV, (18 June 2004); doi: 10.1117/12.529797
Show Author Affiliations
J. Quincy Brown, Louisiana Tech Univ. (United States)
Suruchi Chopra, Louisiana Tech Univ. (United States)
Patrick S. Grant, Louisiana Tech Univ. (United States)
Michael J. McShane, Louisiana Tech Univ. (United States)

Published in SPIE Proceedings Vol. 5325:
Optical Diagnostics and Sensing IV
Gerard L. Cote; Alexander V. Priezzhev, Editor(s)

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