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Proceedings Paper

Flexible coupling of a waveguide detector with a microscale field flow fractionation device
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Paper Abstract

This paper describes a simple packaging method to fabricate microfluidic channels and obtain an optical detection interface for micro analysis systems. Specifically, this work reports on efforts to develop new methods for simple, fast and reliable design and fabrication of microscale field flow fractionation (FFF) based biological analysis systems. This modular detector interface results in a 38 nl detection region. Detector characterization is carried out to evaluate important figures of merit such as sensitivity, S/N ratio, and limit of detection. Plate height, a primary performance criterion for field flow fractionation is determined and compared with an on-chip detector. The developed system allow for a plug-and-play approach to the optical interface has resulted in flexibility in operation and increased robustness of the micro device.

Paper Details

Date Published: 23 December 2003
PDF: 8 pages
Proc. SPIE 5345, Microfluidics, BioMEMS, and Medical Microsystems II, (23 December 2003); doi: 10.1117/12.529377
Show Author Affiliations
Himanshu J. Sant, Univ. of Utah (United States)
Bruce K. Gale, Univ. of Utah (United States)

Published in SPIE Proceedings Vol. 5345:
Microfluidics, BioMEMS, and Medical Microsystems II
Peter Woias; Ian Papautsky, Editor(s)

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