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Proceedings Paper

Demonstration of the true-reflection OCT imaging algorithm on a heterogeneous multilayered structure
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Paper Abstract

A recently developed analytical optical coherence tomography (OCT) model (L. Thrane et al., J. Opt. Soc. Am. A 17, 484 (2000)) allows the extraction of optical scattering parameters therby enabling attenuation compensation in OCT images. By expanding this theoretical model, we have delevoped a new method for extracting optical scattering parameters from multi-layered tissue structures in vivo. To verify this, we have used a Monte Carlo (MC) OCT model as a numerical phantom to simulate the OCT signal for heterogeneous multi-layered tissue. Excellent agreement is obtained between the extracted values for the optical scattering properties of the different layers and the corresponding input reference values of the MC simulation, which demonstrates its feasibility for in vivo applications. This is the first time such a verification has been obtained, which holds promise of expanding the funtional imaging capabilities of OCT.

Paper Details

Date Published: 1 July 2004
PDF: 6 pages
Proc. SPIE 5316, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII, (1 July 2004); doi: 10.1117/12.529195
Show Author Affiliations
Lars Thrane, Riso National Lab. (Denmark)
Michael H. Frosz, Riso National Lab. (Denmark)
COM, Danmarks Tekniske Univ. (Denmark)
Andreas Tycho, OCT Innovation ApS (Denmark)
Thomas Martini Jorgensen, Riso National Lab. (Denmark)
Harold T. Yura, The Aerospace Corp. (United States)
Peter Eskil Andersen, Riso National Lab. (Denmark)

Published in SPIE Proceedings Vol. 5316:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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