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Proceedings Paper

Nanofabrication of structures for cell engineering
Author(s): Chris D. W. Wilkinson; Stephen Thoms; Douglas S. Macintyre; Adam S. G. Curtis; Mathis Riehle; Nicolaj Gadegaard
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Paper Abstract

Cell engineering is concerned with the combination of engineered materials with biological cells to create useful devices. Cells in the body are organised spatially and this organisation is reflected in the shapes of the cells themselves and in how they are positioned relative to their neighbours. A necessary first step in re-growing cells to form a tissue-like implant is to re-create this original pattern in the re-grown cells. A brief account is given of the effects of topographic and chemical patterning on the behaviour of cells. The methods by which such patterning can be transferred into materials suitable for cell and tissue engineering are given. The advantages of using mechanical transfer in one of its many forms for this purpose are stressed.

Paper Details

Date Published: 15 October 2003
PDF: 9 pages
Proc. SPIE 5220, Nanofabrication Technologies, (15 October 2003); doi: 10.1117/12.509749
Show Author Affiliations
Chris D. W. Wilkinson, Glasgow Univ. (United Kingdom)
Stephen Thoms, Glasgow Univ. (United Kingdom)
Douglas S. Macintyre, Glasgow Univ. (United Kingdom)
Adam S. G. Curtis, Glasgow Univ. (United Kingdom)
Mathis Riehle, Glasgow Univ. (United Kingdom)
Nicolaj Gadegaard, Glasgow Univ. (United Kingdom)

Published in SPIE Proceedings Vol. 5220:
Nanofabrication Technologies
Elizabeth A. Dobisz, Editor(s)

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