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Proceedings Paper

Smart drug delivery system based on pyrotechnical actuation
Author(s): Manel Puig-Vidal; Jaime Lopez; Pere Miribel; Josep Samitier-Marti; Carole Rossi; Axel Berthold
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Paper Abstract

A smart drug delivery injector microsystem is presented based on small pyrotechnics to impulse drugs to be injected to a human being. The proposal refers to a feasibility demonstration of the technology for pharmaceutical chips. These chips would be around some cm2 in section and will be able to inject a drug into de subject skin responding to an electrical signal. The product derived from this activity will be useful for astronaut's health, being able to administrate emergency doses of products (for instance cardio-tonic or hypoallegic drugs) enough to survive an emergency situation (as it can be a heart attack during EVA). The system can also be used for easy administration of drugs needed for physiological research. The usefulness of the device in terrestrial applications has no doubt, allowing remote administration of drugs to patients whose biomedical parameters are remotely monitored. The concept proposed here is new in combining the idea of pharmaceutical chip with the ultrasonic droplet technology and the use of pyrotechnics to provide energy to the drug to be injected. The proposed Drug Injector Microsystem is based on 2 main blocks:- Micropyrotechnic system: defines the ignition part based on pyrotechnic.- Microfluidic system: defines the drug injection part. This part is also divided in different critical parts: Expansion chamber, membrane or piston, drug reservoir and a needle. Different sensors are placed on the expansion chamber of microfluidic system and on the micropyrotechnic system. A complete electronic module is implemented with a PC interface to define flexible and user friendly experiences showing the smart drug delivery injector microsystem principle.

Paper Details

Date Published: 18 April 2003
PDF: 10 pages
Proc. SPIE 5119, Bioengineered and Bioinspired Systems, (18 April 2003); doi: 10.1117/12.501509
Show Author Affiliations
Manel Puig-Vidal, SIC-Univ. de Barcelona (Spain)
Jaime Lopez, SIC-Univ. de Barcelona (Spain)
Pere Miribel, SIC-Univ. de Barcelona (Spain)
Josep Samitier-Marti, SIC-Univ. de Barcelona (Spain)
Carole Rossi, LAAS-CNRS (France)
Axel Berthold, LAAS-CNRS (France)

Published in SPIE Proceedings Vol. 5119:
Bioengineered and Bioinspired Systems
Angel Rodriguez-Vazquez; Derek Abbott; Ricardo Carmona, Editor(s)

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