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Proceedings Paper

Characterization of the autofluorescence of normal and tumoral esophageal epithelium cells
Author(s): Sandrine Villette; Genevieve Bourg-Heckly; Sophie Pigaglio; Pierre Validire; Alexei Grichine; Christine Vever-Bizet
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Paper Abstract

The objectives of this study are to characterize the autofluorescence spectra of normal and tumoral esophageal epithelial cells and to link the cellular spectra with a data basis of in vivo tissular spectra. Our preliminary results show that no difference in spectral distribution can be observed between squamous cell carcinoma, adenocarcinoma and normal cells. A statistical significant difference is observed between the average intensity of the raw spectra of the different cell types. Nucleus autofluorescence presents the same spectral shape as cytoplasm, but with lower intensity.

Paper Details

Date Published: 8 October 2003
PDF: 9 pages
Proc. SPIE 5141, Diagnostic Optical Spectroscopy in Biomedicine II, (8 October 2003); doi: 10.1117/12.500226
Show Author Affiliations
Sandrine Villette, Univ. Pierre et Marie Curie (France)
Genevieve Bourg-Heckly, Univ. Pierre et Marie Curie (France)
Sophie Pigaglio, Univ. Pierre et Marie Curie (France)
Pierre Validire, Institut Mutualiste Montsouris (France)
Alexei Grichine, Ctr. de Biophysique Moleculaire, CNRS (France)
CNRS, Orleans (France)
Christine Vever-Bizet, Museum National d'Histoire Naturelle (France)
CNRS UMR 8646 (France)

Published in SPIE Proceedings Vol. 5141:
Diagnostic Optical Spectroscopy in Biomedicine II
Georges A. Wagnieres, Editor(s)

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