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Proceedings Paper

Short-pulse laser propagation through tissues
Author(s): Champak Das; Ashish Trivedi; Kunal Mitra; Tuan Vo-Dinh
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Paper Abstract

An experimental and numerical study is performed to analyze short pulse laser propagation through tissue phantoms without and with inhomogeneities / tumors imbedded in it. Short pulse laser probing techniques has distinct advantages over conventional very large pulse width or cw lasers primarily due to the additional information conveyed about the tissue interior by the temporal variation of the observed signal. Both the scattered temporal transmitted and reflected optical signals are measured experimentally using a streak camera for samples irradiated with a short pulse laser source. Parametric study involving different scattering and absorption coefficients of tissue phantoms and inhomogeneities as well as the detector position and orientation is performed. The temporal and spatial profiles of the scattered optical signals are compared with the numerical modeling results obtained by solving the transient radiative transport equation using discrete ordinates technique.

Paper Details

Date Published: 22 July 2003
PDF: 11 pages
Proc. SPIE 4958, Advanced Biomedical and Clinical Diagnostic Systems, (22 July 2003); doi: 10.1117/12.497340
Show Author Affiliations
Champak Das, Florida Institute of Technology (United States)
Ashish Trivedi, Florida Institute of Technology (United States)
Kunal Mitra, Florida Institute of Technology (United States)
Tuan Vo-Dinh, Oak Ridge National Lab. (United States)

Published in SPIE Proceedings Vol. 4958:
Advanced Biomedical and Clinical Diagnostic Systems
Tuan Vo-Dinh; Warren S. Grundfest M.D.; David A. Benaron M.D.; Gerald E. Cohn, Editor(s)

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