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Proceedings Paper

Effects of copper vapor laser (CVL) on mice skin: histologic evaluation of damage and tissue stimulation
Author(s): Syllene Nunes; E. Moreno; H. Oliveira; J. Osaka; G. Salvador; N. Michalany; E. Tolosa
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Paper Abstract

This study was to evaluate the effects of the CVL with low energy and short pulse widths. 18 female mice, C57BL/6 (9-11 weeks old) were distributed into four groups. The control group (CG) wasn't exposed to laser beam . Group L1 had 2 laser expositions with 24 hours gap between them (0.5W). Group L2 had 3 expositions (0.5W and 0.25W) and group L3 had 4 expositions (0.25 W). It was used a CVL prototype (5lOnm, 13 Khz, pulse width of 20 ms and spot size of 0.8cm). 7 days after last laser pulse no groups presented actinic keratosis, tumors or collagen changes. CVL had effective action on pilosebaceous units. High energy with few short pulses induced hair follicles proliferation while low energy with many repetitive short pulses showed increased and specific tissue damage besides hair plugging.

Paper Details

Date Published: 15 October 2002
PDF: 7 pages
Proc. SPIE 4903, Laser Florence 2001: A Window on the Laser Medicine World, (15 October 2002); doi: 10.1117/12.486603
Show Author Affiliations
Syllene Nunes, Univ. of São Paulo (Brazil)
E. Moreno, Navy Ctr. of Technology (Brazil)
H. Oliveira, Navy Ctr. of Technology (Brazil)
J. Osaka, Federal Univ. of São Paulo (Brazil)
G. Salvador, Univ. of São Paulo (Brazil)
N. Michalany, Federal Univ. of São Paulo (Brazil)
E. Tolosa, Univ. of São Paulo (Brazil)


Published in SPIE Proceedings Vol. 4903:
Laser Florence 2001: A Window on the Laser Medicine World
Leonardo Longo; Alfons G. Hofstetter; Mihail-Lucian Pascu; Wilhelm R. A. Waidelich, Editor(s)

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