This study investigated a bilayer gastrointestinal normal tissue (including mucosa and submucosa layers) and a cancerous tissue model (including adenoma and submucosa layers), and reconstructed their Laser-Induced Autofluorescence (LIAF) spectra by Monte-Carlo simulation. The good correlation between the reconstructed spectra and experimental spectra suggested that Monte-Carlo simulation can accurately describe the generation and transportation of fluorescence in tissue and therefore can detect cancerous tissue by revealing the real biophysical and biochemical information of tissue.

Date Published: 12 September 2002
PDF: 4 pages
Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.483003

Published in SPIE Proceedings Vol. 4916:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment
Britton Chance; Mingzhe Chen; Gilwon Yoon, Editor(s)