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Proceedings Paper

Construction of tissue autofluorescence spectra by Monte-Carlo simulation
Author(s): Xiaodong Chen; Hongbo Xie; Zhi Xu; Daoyin Yu
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Paper Abstract

This study investigated a bilayer gastrointestinal normal tissue (including mucosa and submucosa layers) and a cancerous tissue model (including adenoma and submucosa layers), and reconstructed their Laser-Induced Autofluorescence (LIAF) spectra by Monte-Carlo simulation. The good correlation between the reconstructed spectra and experimental spectra suggested that Monte-Carlo simulation can accurately describe the generation and transportation of fluorescence in tissue and therefore can detect cancerous tissue by revealing the real biophysical and biochemical information of tissue.

Paper Details

Date Published: 12 September 2002
PDF: 4 pages
Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.483003
Show Author Affiliations
Xiaodong Chen, Tianjin Univ. (China)
Hongbo Xie, Tianjin Univ. (China)
Zhi Xu, Tianjin Univ. (China)
Daoyin Yu, Tianjin Univ. (China)

Published in SPIE Proceedings Vol. 4916:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment
Britton Chance; Mingzhe Chen; Gilwon Yoon, Editor(s)

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