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[Ca2+]i and MCLA-enhanced ultraweak chemiluminescence of macrophages irradiated with low-intensity He-Ne laser
Author(s): Chaoyang Xu; Da Xing; Shici Tan; Xian Li
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Paper Abstract

Low intensity He-Ne laser therapy (eg: intravascular laser irradiation on blood, ILIB) has been wildly used to treat with some illness in clinic but the mechanism remain obscure. Laser power, the irradiation time and the irradiation dose were changed. Laser scanning confocal microscope (LSCM) was used to real-time research the effort of low intensity irradiation on {Ca2+}I in mouse marcophage and single photon counter device (SPC) was used to detect the MCLA enhanced chemiluminescence of macrophage irradiation with low intensity He-Ne laser. Proper dose of low intensity He-Ne laser irradiation can increase the [Ca2+]I of the macrophage and immunocompetence of macrophage effectively. Laser power of 0.16mw is more effect to increase the [Ca2+]i than laser power of 0.40mw. The [Ca2+]i is markedly different even the irradiation dose or the irradiation time is same. Both the irradiation dose and laser power are key factor for the change of [Ca2+]i and immunocopetance of macrophage. Activating ammuno-system of body is one of the very important mechanisms of Low-intensity He-Ne laser therapy.

Paper Details

Date Published: 12 September 2002
PDF: 8 pages
Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.483002
Show Author Affiliations
Chaoyang Xu, South China Normal Univ. (China)
Da Xing, South China Normal Univ. (China)
Shici Tan, South China Normal Univ. (China)
Xian Li, South China Normal Univ. (China)

Published in SPIE Proceedings Vol. 4916:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment
Britton Chance; Mingzhe Chen; Gilwon Yoon, Editor(s)

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