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Proceedings Paper

Application of LED imager for breast cancer diagnosis
Author(s): Jun Zhang; Yuanqing Lin; Shoko Nioka; Nancy O'Connor; Brian Czerniecki; Emily F. Conant; Britton Chance
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Paper Abstract

This paper focuses on breast cancer diagnosis using the newly developed low-noise threewavelength (?=730nm, 805nm and 850nm) NIR light emitting diode (LED) continuous-wave (CW) imager. The NIR CW imager has its advantage of simplicity, and potential for a portable instrument. The imaging rate is 5 frame/second. The signal to noise ratio is larger than 2000 when measuring at a breast model ( ?a=0.04/cm, ?'= 8/cm), which corresponds to 4x 10-4 optical density (OD) error. Phantom test was carried out, and indicated good localization of heterogeneity. It was known that cancer has more blood concentration and de-oxygenation than normal tissue, which is the principle of breast cancer detection using NIR spectroscopy. Clinical results of breast cancer studies will be presented. Keywords: LED, Breast Cancer Imaging, CW

Paper Details

Date Published: 12 September 2002
PDF: 7 pages
Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); doi: 10.1117/12.482933
Show Author Affiliations
Jun Zhang, Univ. of Pennsylvania (United States)
Yuanqing Lin, Univ. of Pennsylvania (United States)
Shoko Nioka, Univ. of Pennsylvania (United States)
Nancy O'Connor, Univ. of Pennsylvania Hospital (United States)
Brian Czerniecki, Univ. of Pennsylvania Hospital (United States)
Emily F. Conant, Univ. of Pennsylvania Hospital (United States)
Britton Chance, Univ. of Pennsylvania (United States)

Published in SPIE Proceedings Vol. 4916:
Optics in Health Care and Biomedical Optics: Diagnostics and Treatment
Britton Chance; Mingzhe Chen; Gilwon Yoon, Editor(s)

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