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Proceedings Paper

Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators
Author(s): Andrzej Krol; David H. Feiglin; K. R. Gangal; Ioana L. Coman; Roberto B. Salgado; Edward D. Lipson; Deborah A. Karczewski; Frank Deaver Thomas
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Paper Abstract

Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT ddata acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.

Paper Details

Date Published: 2 May 2003
PDF: 7 pages
Proc. SPIE 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, (2 May 2003);
Show Author Affiliations
Andrzej Krol, SUNY/Upstate Medical Univ. (United States)
David H. Feiglin, SUNY/Upstate Medical Univ. (United States)
K. R. Gangal, Syracuse Univ. (United States)
Ioana L. Coman, SUNY/Upstate Medical Univ. (United States)
Syracuse Univ. (United States)
Ithaca College (United States)
Roberto B. Salgado, Dillard Univ. (United States)
Edward D. Lipson, SUNY/Upstate Medical Univ. (United States)
Syracuse Univ. (United States)
Deborah A. Karczewski, SUNY/Upstate Medical Univ. (United States)
Frank Deaver Thomas, SUNY/Upstate Medical Univ. (United States)

Published in SPIE Proceedings Vol. 5031:
Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications
Anne V. Clough; Amir A. Amini, Editor(s)

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