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Proceedings Paper

Unilateral pleural effusion in an animal model: evaluation of lung function with EBCT
Author(s): Wolfgang A. Recheis; Leo Pallwein; Peter Soegner; Ralph Faschingbauer; Georg Schmidbauer; Axel Kleinsasser; Alexander Loeckinger; Christoph Hoermann; Dieter zur Nedden
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Paper Abstract

The purpsoe was to evaluate the influence of a right-sided pleural effusion on the lung aeration dynamics in the respiratory cycle during pressure controlled ventilation. Pleural effusion was simulated by infusion of 3% gelatin into the pleural cavity in steps of 300ml totaling 1200ml in four anesthetized pigs. After each step, volume scans and respirator gated 50ms scans at a constant table position (carina niveau) were taken. The dynamic changes of the previously defined air-tissue ratios (in steps of 100HU) were evaluated in three separate regions of left and right lung: a ventral, an intermediate and a dorsal area. The affected side revealed dramatic alveolar collapse. There was a shift of the lung density to higher air-tissue ratios (+200HU) but showing the same air-tissue ratio dynamics. A slight lateral shift of 32mm (±14mm) the mediastinum was measured. The unaffected side showed no increase in the air-tissue ratios caused by hyperinflation but an increase of density due to mediastinal shift. Air-tissue ratio dynamics remained unchanged on the unaffected side compared to baseline measurements. We visualized the ventilation mismatch caused by pleural effusion. The contra-lateral lung is not affected by unilateral pleural effusion. Pressure controlled ventilation prevents hyper-inflation of non-dependent lung areas.

Paper Details

Date Published: 2 May 2003
PDF: 9 pages
Proc. SPIE 5031, Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications, (2 May 2003); doi: 10.1117/12.480319
Show Author Affiliations
Wolfgang A. Recheis, Univ. Hospital Innsbruck (Austria)
Leo Pallwein, Univ. Hospital Innsbruck (Austria)
Peter Soegner, Univ. Hospital Innsbruck (Austria)
Ralph Faschingbauer, Univ. Hospital Innsbruck (Austria)
Georg Schmidbauer, Univ. Hospital Innsbruck (Austria)
Axel Kleinsasser, Univ. Hospital Innsbruck (Austria)
Alexander Loeckinger, Univ. Hospital Innsbruck (Austria)
Christoph Hoermann, Univ. Hospital Innsbruck (Austria)
Dieter zur Nedden, Univ. Hospital Innsbruck (Austria)

Published in SPIE Proceedings Vol. 5031:
Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications
Anne V. Clough; Amir A. Amini, Editor(s)

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