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Proceedings Paper

Finger joint imaging by laser transillumination computed tomography based on coherent detection imaging method
Author(s): Shinji Tanosaki; Yoshiaki Sasaki; Michiaki Takagi; Akira Ishikawa; Jota Suzuki; Ryota Emori; Hiroki Inage; Tetsuya Yuasa; Hiroshi Taniguchi; Balasigamani Devaraj; Takao Akatsuka
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Paper Abstract

In this research, we investigate the imaging properties of tansillumination laser CT system based on the coherent detection imaging (CDI) method, for early diagnosis of rheumatoid arthritis, from the viewpoints of morphological and quantitative imaging. First, to investigate the morphological imaging ability, the index finger PIP joint of a healthy volunteer was imaged with the laser CT, X-ray CT, and MRI. By comparison of these images, we present that the laser CT delineates the bone region with high spatial resolution of sub-millimeters. Next, to investigate the quantitative imaging, three kinds of the physical phantoms simulating bone, made from polyurethane including different concentrations of CaCO3, were imaged. We present that quantitative measurement is possible by demonstrating a satisfactory linear relationship between the averaged pixel value of the reconstructed images and the actual concentrations. These results demonstrate the feasibility of early diagnosis for rheumatoid arthritis.

Paper Details

Date Published: 29 July 2003
PDF: 9 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478226
Show Author Affiliations
Shinji Tanosaki, Yamagata Univ. (Japan)
Yoshiaki Sasaki, Yamagata Univ. (Japan)
Michiaki Takagi, Yamagata Univ. (Japan)
Akira Ishikawa, Yamagata Univ. (Japan)
Jota Suzuki, Yamagata Univ. (Japan)
Ryota Emori, Yamagata Univ. (Japan)
Hiroki Inage, Yamagata Univ. (Japan)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Hiroshi Taniguchi, Iwate Univ. (Japan)
Balasigamani Devaraj, New Focus Corp. (United States)
Takao Akatsuka, Yamagata Univ. (Japan)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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