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Proceedings Paper

Method to measure the optical properties of small volumes of biological tissues
Author(s): Fabrizio Martelli; Samuele del Bianco; Giovanni Zaccanti
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Paper Abstract

The method consists in measuring the perturbation provoked by a small volume (0.2-1 ml) of tissue on light propagating through a medium of known optical properties. The absorption and the reduced scattering coefficient of the medium are retrieved from multidistance continuous wave measurements of transmittance. The inversion procedure is based on the solution of the diffusion equation obtained with a perturbative approach. The method has been validated with Monte Carlo results. Experimental results are reported for various kind of tissue. The results obtained shows that the method is particularly effective for low absorbing tissues.

Paper Details

Date Published: 29 July 2003
PDF: 6 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478218
Show Author Affiliations
Fabrizio Martelli, INFM, Univ. degli Studi di Firenze (Italy)
Samuele del Bianco, INFM, Univ. degli Studi di Firenze (Italy)
Giovanni Zaccanti, INFM, Univ. degli Studi di Firenze (Italy)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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