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Proceedings Paper

Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma
Author(s): Jun Zhang; Tao Tu; Ulas Sunar; Xavier Intes; Shoko Nioka; Zhihong Zhang; Alex Kilger; Robert A. Lustig; Laurie A. Loevner; Britton Chance
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Paper Abstract

Near Infrared Spectroscopy (NIRS) has been widely used in cancer imaging spectroscopy because cancer tissue has more blood volume and less oxygen than normal tissue. The neck squamous cell carcinoma is ideal for our study because it’s a surface mass can be easily feel through the skin. We use a simple homodyne phase modulation system, In-phase and Quadrature Phase (I&Q) Detection system, to study the curative effect of therapy in neck cancer patients. Clinical treatment includes mainly chemical and radiation therapy, both of which alter the blood volume and the oxygenation saturation in cancer tissue. The I&Q detection system is capable of the quantification measurement of those biological changes. In this paper, we will simply introduce the I&Q detection system’s principle and constitution, and mainly explain the analysis of patients’ data.

Paper Details

Date Published: 29 July 2003
PDF: 6 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.478177
Show Author Affiliations
Jun Zhang, Univ. of Pennsylvania (United States)
Tao Tu, Univ. of Pennsylvania (United States)
Ulas Sunar, Univ. of Pennsylvania (United States)
Xavier Intes, Univ. of Pennsylvania (United States)
Shoko Nioka, Univ. of Pennsylvania (United States)
Zhihong Zhang, Univ. of Pennsylvania (United States)
Alex Kilger, Hospital of Univ. of Pennsylvania (United States)
Robert A. Lustig, Hospital of Univ. of Pennsylvania (United States)
Laurie A. Loevner, Hospital of Univ. of Pennsylvania (United States)
Britton Chance, Univ. of Pennsylvania (United States)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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