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Proceedings Paper

Near-infrared measurements of hemodynamic and oxygenation changes on the frontal cortex during breath holding, hyperventilation, and natural sleep
Author(s): Tommi EJ. Noponen; Kalle Kotilahti; Jussi Toppila; Ilkka T. Nissila; Tapani Salmi; Timo T. Kajava; Toivo E. Katila
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Paper Abstract

We have developed a frequency-domain near-infrared device suitable for physiological studies in human. In this work, a four-channel configuration of the instrument is applied to monitor hemodynamic and oxygenation changes in the frontal cortex of volunteers during different ventilation tasks. We use four different source-receiver separations (2, 3, 4, and 5 cm) and three wavelengths (760, 808, and 830 nm) to test the sensitivity of these parameters to cardiovascular and metabolic changes. Low-frequency oscillations (~ 0.02 Hz) and variations in heart rate during different ventilation tasks are investigated as well. We also study physiological changes during natural sleep using the frequency-domain instrument simultaneously with a polysomnography system containing a pulse oximeter. Our results indicate that hemodynamic and oxygenation changes in the frontal cortex during natural sleep can be detected using near-infrared measurements.

Paper Details

Date Published: 29 July 2003
PDF: 10 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.476809
Show Author Affiliations
Tommi EJ. Noponen, Helsinki Univ. of Technology (Finland)
Kalle Kotilahti, Helsinki Univ. of Technology (Finland)
Jussi Toppila, Helsinki Univ. Central Hospital (Finland)
Ilkka T. Nissila, Helsinki Univ. of Technology (Finland)
Tapani Salmi, Helsinki Univ. Central Hospital (Finland)
Timo T. Kajava, Helsinki Univ. of Technology (Finland)
Toivo E. Katila, Helsinki Univ. of Technology (Finland)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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