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Proceedings Paper

Clinical evaluation of a near-infrared tissue spectrometer in peripheral vascular disease
Author(s): Xuefeng Cheng; Jian-Min Mao; Xiaorong Xu; Mohamed Elmandjra; Robin Bush; Linda Christenson; Bill O'Keefe; John Bry
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Paper Abstract

We report results of a feasibility clinical evaluation of the near-infrared Photonify Tissue Spectrometer in detection of peripheral vascular disease (PVD). In the evaluation, using a blood pressured cuff, we measure changes in oxygen saturation (StO2) during a temporary occlusion of blood inflow. We use the post-occlusive StO2 recovery rate and the time needed for 80% recovery as parameters to differentiate healthy subjects from subjects with PVD, and obtained high diagnostic accuracy in 19 subjects enrolled in the clinical evaluation. This may suggest that the tissue spectrometer could be useful in diagnosis of PVD.

Paper Details

Date Published: 29 July 2003
PDF: 6 pages
Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); doi: 10.1117/12.476551
Show Author Affiliations
Xuefeng Cheng, Photonify Technologies, Inc. (United States)
Jian-Min Mao, Photonify Technologies, Inc. (United States)
Xiaorong Xu, Photonify Technologies, Inc. (United States)
Mohamed Elmandjra, Photonify Technologies, Inc. (United States)
Robin Bush, Photonify Technologies, Inc. (United States)
Linda Christenson, Photonify Technologies, Inc. (United States)
Bill O'Keefe, Alameda County Medical Ctr. (United States)
John Bry, Alta Bates Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 4955:
Optical Tomography and Spectroscopy of Tissue V
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva M. Sevick-Muraca, Editor(s)

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