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Proceedings Paper

Dynamic response of ensemble neurons to pulsed optical and electrical excitation in vivo and in vitro
Author(s): Garif G. Akchurin; George A. Seleverstov; Tatyana G. Kamenskih; George G. Akchurin; Olga A. Bondarenko
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Paper Abstract

The nonlinear response of the Hodgkin-Huxley model neuron with external electrical pulsed was investigated. Dynamic response of somatic frog nerve on electrical pulsed duration was study in vitro. Transcutaneous millisecond of excitation of the ganglion cell of the human retina by electric uses is used for diagnosis, determination of the extent of optic nerve damage, and also partial restoration of visual function in patients with glaucoma, myopia and different types of optic nerve atrophy. Correlation between the threshold of phosphen formation and duration of the stimulating electric pulses was determined experimentally in normal eyes and in eyes with various pathologies. Comparison of optical and electrical scintillating frequency gives information about the dynamic processes in the normal and pathological retina.

Paper Details

Date Published: 16 July 2002
PDF: 6 pages
Proc. SPIE 4707, Saratov Fall Meeting 2001: Optical Technologies in Biophysics and Medicine III, (16 July 2002); doi: 10.1117/12.475615
Show Author Affiliations
Garif G. Akchurin, Saratov State Univ. (Russia)
George A. Seleverstov, Saratov State Medical Univ. (Russia)
Tatyana G. Kamenskih, Saratov State Medical Univ. (Russia)
George G. Akchurin, Saratov State Univ. (Russia)
Olga A. Bondarenko, Saratov State Univ. (Russia)

Published in SPIE Proceedings Vol. 4707:
Saratov Fall Meeting 2001: Optical Technologies in Biophysics and Medicine III
Valery V. Tuchin, Editor(s)

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