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Proceedings Paper

Microfabrication of hydrogels for biomedical applications
Author(s): Tianyue Yu; Federica Chiellini; Dirk Schmaljohan; Roberto Solaro; Christopher Kemper Ober
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Paper Abstract

Hydrogels have gained general acceptance as biocompatible materials and are the basis of many promising applications in tissue engineering, drug release formulations and biosensors. Polymer processing techniques that can generate miniature hydrogel microstructures are not only critical as scaffolds for tissue re-growth but also very effective for increasing the efficiency of drug delivery and biosensors. Our approach is to use both optical and soft lithographic methods to microfabricate hydrogels. In this paper, we describe a photolithographic process to pattern hydrogel materials and analyze factors influencing sensitivity and lateral resolution. The model system we are investigating is based on 2-hydroxyethyl methacrylate (HEMA), which is well known for its non-toxicity and its widespread use in the contact lens industry.

Paper Details

Date Published: 24 July 2002
PDF: 7 pages
Proc. SPIE 4690, Advances in Resist Technology and Processing XIX, (24 July 2002); doi: 10.1117/12.474288
Show Author Affiliations
Tianyue Yu, Cornell Univ. (United States)
Federica Chiellini, Univ. di Pisa (Italy)
Dirk Schmaljohan, IPF Dresden eV (Germany)
Roberto Solaro, Univ. di Pisa (Italy)
Christopher Kemper Ober, Cornell Univ. (United States)

Published in SPIE Proceedings Vol. 4690:
Advances in Resist Technology and Processing XIX
Theodore H. Fedynyshyn, Editor(s)

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