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Proceedings Paper

Drug effects on functional structures in isolated perfused pig heart
Author(s): Tobias Trinks; Robert Rauh M.D.; Michael Hiller; Manfred D. Kessler
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Paper Abstract

Until today monitoring of immediate drug tissue interaction in living organs is an unsolved problem. However, for the development of new drugs and the improvement of medical therapy outcome it would be helpful to get new tools to visualize drug effects on tissue directly. With the EMPHO II SSK and a 3D-scanning device we detected changes of functional structures in an isolated perfused pig heart model after adding commonly used drugs like verapamil, nitroglycerin and salviae miltiorrhizae (Chinese herbal drug). In the paper the results are presented.

Paper Details

Date Published: 5 June 2002
PDF: 8 pages
Proc. SPIE 4623, Functional Monitoring and Drug-Tissue Interaction, (5 June 2002); doi: 10.1117/12.469453
Show Author Affiliations
Tobias Trinks, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Robert Rauh M.D., Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Michael Hiller, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Manfred D. Kessler, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)

Published in SPIE Proceedings Vol. 4623:
Functional Monitoring and Drug-Tissue Interaction
Manfred D. Kessler; Gerhard J. Mueller, Editor(s)

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