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Proceedings Paper

Quantitative optical differences between 2D images of human myocardium and liver tissue
Author(s): Manfred D. Kessler; Robert Rauh M.D.; Michael Hiller; Tobias Trinks; Michael Singer
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Paper Abstract

It is attractive to perform a kind of comparative physiology between two completely different organs. The heart is an organ able to suck blood from vena cava into atria and pump the blood from ventricles through aorta into periphery while liver is a kind of biochemical factory. Sizeable morphological differences exist between the two organs. However, many similarities are found by optical sensors on the level of regulation such as distribution of blood flow in supply units, decrease of oxygen uptake under conditions of activity or rest. The shape of histograms of HbO2 is almost equal in all organs, while the mean values of intracapillary HbO2 reveal differences thus shifting the histogram more or less. For human life the diffusive masstransfer between capillaries and cells is of extraordinary importance. The multicomponent system of this microcosm is not really known. However, for the opening of this unknown world of endothelial cells of capillaries and cells of organs optical sensor systems are now available for investigations of a very great number of diseases.

Paper Details

Date Published: 5 June 2002
PDF: 5 pages
Proc. SPIE 4623, Functional Monitoring and Drug-Tissue Interaction, (5 June 2002); doi: 10.1117/12.469451
Show Author Affiliations
Manfred D. Kessler, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Robert Rauh M.D., Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Michael Hiller, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Tobias Trinks, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)
Michael Singer, Friedrich-Alexander-Univ. Erlangen-Nuernberg (Germany)

Published in SPIE Proceedings Vol. 4623:
Functional Monitoring and Drug-Tissue Interaction
Manfred D. Kessler; Gerhard J. Mueller, Editor(s)

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