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Proceedings Paper

Blood pool agent contrast-enhanced MRA: level-set-based artery-vein separation
Author(s): Cornelis M. van Bemmel; Luuk J. Spreeuwers; Bert Verdonck; Max A. Viergever; Wiro J. Niessen
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Paper Abstract

Blood pool agents (BPAs) for contrast-enhanced magnetic resonance angiography (CE-MRA) allow prolonged imaging times for higher contrast and resolution by imaging during the steady-state when the contrast agent is distributed through the complete vascular system. However, simultaneous venous and arterial enhancement hampers interpretation. It is shown that arterial and venous segmentation in this equilibrium phase can be achieved if the central arterial axis (CAA) and central venous axis (CVA) are known. Since the CAA can not straightforwardly be obtained from the steady-state data, images acquired during the first-pass of the contrast agent can be utilized to determine the CAA with minimal user initialization. Utilizing the CAA to provide a rough arterial segmentation, the CVA can subsequently be determined from the steady-state dataset. The final segmentations of the arteries and veins are achieved by simultaneously evolving two level-sets in the steady-state dataset starting from the CAA and CVA.

Paper Details

Date Published: 9 May 2002
PDF: 12 pages
Proc. SPIE 4684, Medical Imaging 2002: Image Processing, (9 May 2002); doi: 10.1117/12.467112
Show Author Affiliations
Cornelis M. van Bemmel, Univ. Medical Ctr. Utrecht (Netherlands)
Luuk J. Spreeuwers, Univ. Medical Ctr. Utrecht (Netherlands)
Bert Verdonck, Philips Medical Systems (Netherlands)
Max A. Viergever, Univ. Medical Ctr. Utrecht (Netherlands)
Wiro J. Niessen, Univ. Medical Ctr. Utrecht (Netherlands)

Published in SPIE Proceedings Vol. 4684:
Medical Imaging 2002: Image Processing
Milan Sonka; J. Michael Fitzpatrick, Editor(s)

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