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Proceedings Paper

Diffraction-enhanced imaging: improved contrast and lower dose x-ray imaging
Author(s): Robert A. Lewis; Keith D. Rogers; Christopher J. Hall; Alan P. Hufton; S. Evans; Ralf-Hendrik Menk; Giuliana Tromba; Fulvia Arfelli; Luigi Rigon; Alessandro Olivo; Andrew Evans; Sarah E. Pinder; Elizabeth Jacobs; Ian O. Ellis; David R. Dance
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Paper Abstract

Conventional x-ray imaging relies almost entirely on differences in the absorption of x-rays between tissues to produce contrast. While these differences are substantial between bone and soft tissue, they are very small between different soft tissue types resulting in poor visualization of soft tissues. Diffraction enhanced imaging (DEI) is currently in development by several groups as a new imaging modality that exploits information contained within the x- ray scattering distribution at low angles. We have used the SYRMEP beam line at the Elettra Synchrotron facility in Trieste, Italy to image a variety of tissue specimens, together with several phantoms. Mono-energetic photons in the range 17 keV to 25 keV were used with an analyzer crystal which diffracted the x-rays onto a detector. We have obtained some spectacular images which display remarkable contrast and resolution. The images can be processed to separate the pure absorption and pure refraction effects in a quantitative manner. These images demonstrate that DEI provides tissue morphology information not accessible with conventional radiographic imaging. The contrast caused primarily by refraction as the x-ray passes from one tissue type to another in the specimen is evident. Since x-ray refraction is much less energy dependent than absorption there is considerable potential for extremely low dose imaging. We believe that the potential of this technique is considerable and we present dat to illustrate the quality of the images.

Paper Details

Date Published: 3 May 2002
PDF: 12 pages
Proc. SPIE 4682, Medical Imaging 2002: Physics of Medical Imaging, (3 May 2002); doi: 10.1117/12.465570
Show Author Affiliations
Robert A. Lewis, Monash Univ. (United Kingdom)
Keith D. Rogers, Cranfield Univ. (United Kingdom)
Christopher J. Hall, Daresbury Lab. (United Kingdom)
Alan P. Hufton, Christie Hospital (United Kingdom)
S. Evans, Royal Marsden NHS Trust (United Kingdom)
Ralf-Hendrik Menk, Sincrotrone Trieste SCpA (Italy)
Giuliana Tromba, Sincrotrone Trieste SCpA (Italy)
Fulvia Arfelli, Univ. degli Studi di Trieste (Italy)
Luigi Rigon, Univ. degli Studi di Trieste (Italy)
Alessandro Olivo, Univ. degli Studi di Trieste (Italy)
Andrew Evans, City Hospital Nottingham (United Kingdom)
Sarah E. Pinder, City Hospital Nottingham (United Kingdom)
Elizabeth Jacobs, Queens Medical Ctr. (United Kingdom)
Ian O. Ellis, City Hospital Nottingham (United Kingdom)
David R. Dance, Royal Marsden NHS Trust (United Kingdom)

Published in SPIE Proceedings Vol. 4682:
Medical Imaging 2002: Physics of Medical Imaging
Larry E. Antonuk; Martin Joel Yaffe, Editor(s)

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