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Proceedings Paper

Interferometric fiber-based optical biosensor to measure ultra-small changes in refractive index
Author(s): Taner Akkin; Digant P. Dave; Thomas E. Milner; Henry Grady Rylander III
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Paper Abstract

In many bio-medical optical imaging applications such as monitoring cell and tissue dynamics and imaging of phase objects, ultra-small changes in refractive index must be detected. We describe a fiber-based optical biosensor, which is capable of detecting ultra-small refractive index changes in highly scattering media with high lateral and longitudinal spatial resolution. The system is a dual channel phase-sensitive optical low coherence tomography system that measures relative optical path length differences between the orthogonal modes of the polarization-maintaining fiber.

Paper Details

Date Published: 26 March 2002
PDF: 5 pages
Proc. SPIE 4616, Optical Fibers and Sensors for Medical Applications II, (26 March 2002); doi: 10.1117/12.463805
Show Author Affiliations
Taner Akkin, Univ. of Texas/Austin (United States)
Digant P. Dave, Univ. of Texas/Austin (United States)
Thomas E. Milner, Univ. of Texas/Austin (United States)
Henry Grady Rylander III, Univ. of Texas/Austin (United States)

Published in SPIE Proceedings Vol. 4616:
Optical Fibers and Sensors for Medical Applications II
Israel Gannot, Editor(s)

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