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Proceedings Paper

Two-modality gamma detection of blood volume by camera imaging and nonimaging stethoscope for kinetic studies of cardiovascular control in nuclear medicine
Author(s): Bernard Eclancher; Jacques Chambron; Barbu Dumitresco; Miklos Karman; Agnes Pszota; Atilla Simon; Anna Didon-Poncelet; Jean Demangeat
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Paper Abstract

The quantification of rapid hemodynamic reactions to wide and slow breathing movements has been performed, by two modalities (gamma) -left ventriculography of 99mTc-labeled blood volume, in anterior oblique incidence on standing and even exercising healthy volunteers and cardiac patients. A highly sensitive stethoscope delivered whole (gamma) -counts acquired at 30 msec intervals in a square field of view including the left ventricle, in a one dimensional low resolution imaging mode for beat to beat analysis. A planar 2D (gamma) -camera imaging of the same cardiac area was then performed without cardiac gating for alternate acquisitions during deep inspiration and deep expiration, completed by a 3D MRI assessment of the stethoscope detection field. Young healthy volunteers displayed wide variations of diastolic times and stroke volumes, as a result of enhanced baroreflex control, together with +/- 16% variations of the stethoscope's background blood volume counts. Any of the components of these responses were shifted, abolished or even inverted as a result of either obesity, hypertension, aging or cardiac pathologies. The assessment of breathing control of the cardiovascular system by the beat to beat (gamma) -ventriculography combined with nuclear 2D and 3D MRI imaging is a kinetic method allowing the detection of functional anomalies in still ambulatory patients.

Paper Details

Date Published: 24 April 2002
PDF: 10 pages
Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002); doi: 10.1117/12.463621
Show Author Affiliations
Bernard Eclancher, Univ. Strasbourg (France)
Jacques Chambron, Univ. Strasbourg (France)
Barbu Dumitresco, Univ. Strasbourg (France)
Miklos Karman, National Cardiology Hospital (Hungary)
Agnes Pszota, National Cardiology Hospital (Hungary)
Atilla Simon, National Cardiology Hospital (Hungary)
Anna Didon-Poncelet, Regional Hospital Haguenau (France)
Jean Demangeat, Regional Hospital Haguenau (France)

Published in SPIE Proceedings Vol. 4683:
Medical Imaging 2002: Physiology and Function from Multidimensional Images
Anne V. Clough; Chin-Tu Chen, Editor(s)

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