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Proceedings Paper

CT perfusion: comparison of gamma-variate fit and deconvolution
Author(s): Zhong Min Lin; Scott Pohlman; A. J. Cook II; Shalabh Chandra
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Paper Abstract

The purpose of this paper is to present results of a study comparing CT brain perfusion image calculated using the maximum slope and deconvolution method on data from 32 patients. The 32 patients were organized into two groups. One group was obtained using a 4cc/sec contrast injection rate and 10 sec injection period; the other group was obtained using a 6cc/sec injection rate and 7 sec injection period. All clinical data were analyzed using both the maximum slope and deconvolution methods. Perfusion maps computed from the two methods were reviewed by radiologists. The contrast enhanced CT data were noisy, especially in the white matter area. Our results showed that, for both methods, perfusion maps from 4cc/sec injection were noisier than those using a 6cc/sec injection. However, both 4cc/sec and 6cc/sec produced useful diagnostic images. Our qualitative side-by-side studies also showed that perfusion images from the maximum slope and deconvolution are both clinically useful and substantially equivalent.

Paper Details

Date Published: 24 April 2002
PDF: 8 pages
Proc. SPIE 4683, Medical Imaging 2002: Physiology and Function from Multidimensional Images, (24 April 2002); doi: 10.1117/12.463572
Show Author Affiliations
Zhong Min Lin, Philips Medical Systems (United States)
Scott Pohlman, Philips Medical Systems (United States)
A. J. Cook II, Robinson Memorial Hospital (United States)
Shalabh Chandra, Philips Medical Systems (United States)

Published in SPIE Proceedings Vol. 4683:
Medical Imaging 2002: Physiology and Function from Multidimensional Images
Anne V. Clough; Chin-Tu Chen, Editor(s)

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