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Proceedings Paper

New applications of fiber-optic IR spectroscopy in urologic practice
Author(s): Shmuel E. Cytron; Sergey Kravchick M.D.; Ben-Ami Sela; Evgeny Shulzinger; Irena Vasserman; Yosef Raichlin; Abraham Katzir
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Paper Abstract

The objective of this work was to use infrared (IR) fiberoptic spectroscopy for the analysis of urinary salts. Urine samples were obtained (with no sample preparation) from two groups of patients: 24 stone forming patients, after shock wave lithotripsy, and 24 normal subjects of similar ages. IR absorption measurements were performed in real time, using Fiberoptic Evanescent Wave Spectroscopy system, based on IR transmitting silver halide fibers. The absorption data were compared with the IR spectra of aqueous solutions with known concentrations of known urinary salts. The results were then used for the study of the chemical composition of salts in urine samples and for a quantitative analysis of the concentration of these salts. We established the composition of the stones in 20 of the 24 stone forming patients, based on the characteristic absorption peaks for oxalates, carbonates, urates and phosphates observed in their urinary samples. We also determined the concentrations of these salts in the urine samples with average error of 20 percent.

Paper Details

Date Published: 27 March 2002
PDF: 8 pages
Proc. SPIE 4614, Biomedical Vibrational Spectroscopy II, (27 March 2002); doi: 10.1117/12.460781
Show Author Affiliations
Shmuel E. Cytron, Barzilai Medical Ctr. (Israel)
Sergey Kravchick M.D., Barzilai Medical Ctr. (Israel)
Ben-Ami Sela, Sheba Medical Ctr. (Israel)
Evgeny Shulzinger, Tel Aviv Univ. (Israel)
Irena Vasserman, Tel Aviv Univ. (Israel)
Yosef Raichlin, Tel Aviv Univ. (Israel)
Abraham Katzir, Tel Aviv Univ. (Israel)

Published in SPIE Proceedings Vol. 4614:
Biomedical Vibrational Spectroscopy II
Anita Mahadevan-Jansen; Henry H. Mantsch; Gerwin J. Puppels, Editor(s)

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