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Proceedings Paper

In-vivo blood flow velocity measurements using the self-mixing effect in a fiber-coupled semiconductor laser
Author(s): Marco H. Koelink; M. Slot; Frits F. M. de Mul; Jan Greve; Reindert Graaff; A. C. M. Dassel; Jan G. Aarnoudse
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Paper Abstract

A laser Doppler velocimeter has been developed to measure blood flow velocity in vivo. It consists of a semiconductor laser coupled to a fiber. Laser light is guided into a blood vessel and backscattered light (by red blood cells) is guided back into the laser. The backscattered Doppler shifted light produces an intensity modulation of the laser (self-mixing effect). The beat-frequency of the intensity modulation is related to the Doppler shift of the backscattered light. A model is presented to calculate modulation signals, and results of measurements in vitro and in vivo are shown.

Paper Details

Date Published: 1 August 1991
PDF: 9 pages
Proc. SPIE 1511, Fiber Optic Sensors: Engineering and Applications, (1 August 1991); doi: 10.1117/12.45984
Show Author Affiliations
Marco H. Koelink, Univ. of Twente (Netherlands)
M. Slot, Univ. of Twente (Netherlands)
Frits F. M. de Mul, Univ. of Twente (Netherlands)
Jan Greve, Univ. of Twente (Netherlands)
Reindert Graaff, Univ. Hospital Groningen (Netherlands)
A. C. M. Dassel, Univ. Hospital Groningen (Netherlands)
Jan G. Aarnoudse, Univ. Hospital Groningen (Netherlands)

Published in SPIE Proceedings Vol. 1511:
Fiber Optic Sensors: Engineering and Applications
Anastasius J.A. Bruinsma; Brian Culshaw, Editor(s)

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