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Proceedings Paper

Array biosensor for environmental monitoring
Author(s): Frances S. Ligler; K. E. Sapsford; Y. S. Shubin; J. Lemmond; Chris A. Rowe-Taitt; J. B. Delahanty; Joel P. Golden
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Paper Abstract

The array biosensor is capable of detecting and identifying multiple analytes in multiple samples simultaneously. Using fluorescence immunoassays on a planar waveguide and miniaturized fluidics, the sensor is automated and portable. Assays are sensitive and require 12 minutes to perform. Environmental contaminants in the sample fail to generate false positive or false negative results in tests performed to date. Measurements can be conducted in real time using spots as small as 80 micrometers . The waveguide can be coated with indium tin oxide (ITO) to create a charged field at the surface to further regulate the interaction of sample components with the surface.

Paper Details

Date Published: 22 February 2002
PDF: 5 pages
Proc. SPIE 4576, Advanced Environmental Sensing Technology II, (22 February 2002); doi: 10.1117/12.456949
Show Author Affiliations
Frances S. Ligler, Naval Research Lab. (United States)
K. E. Sapsford, George Mason Univ. (United States)
Y. S. Shubin, Geo-Centers, Inc. (United States)
J. Lemmond, Hofstra Univ. (United States)
Chris A. Rowe-Taitt, Naval Research Lab. (United States)
J. B. Delahanty, Naval Research Lab. (United States)
Joel P. Golden, Naval Research Lab. (United States)

Published in SPIE Proceedings Vol. 4576:
Advanced Environmental Sensing Technology II
Tuan Vo-Dinh; Stephanus Buettgenbach, Editor(s)

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