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Proceedings Paper

Synthesis and surface modification of superparamagnetic nanoparticles for biomedical applications
Author(s): Nathan Kohler; Yong Zhang; Brad Busche; Miqin Zhang
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Paper Abstract

Monodispersed superparamagnetic nanoparticles were synthesized from aqueous iron chloride solutions and were modified with poly(ethylene glycol) self assembled monolayers to improve their dispersion, biocompatibility and intracellular uptake for biomedical applications. Transmission electron micrographs (TEM) and atomic force microscopy (AFM) showed an average particle size of 10-30 nm and confirmed particle dispersion following surface modification with PEG. Fourier transform infrared spectroscopy (FTIR) confirmed the presence of PEG on the nanoparticle surface and the particles were further characterized with electron energy loss spectroscopy (EELS).

Paper Details

Date Published: 4 October 2002
PDF: 8 pages
Proc. SPIE 4810, Properties of Metal Nanostructures, (4 October 2002); doi: 10.1117/12.453767
Show Author Affiliations
Nathan Kohler, Univ. of Washington (United States)
Yong Zhang, Univ. of Washington (United States)
Brad Busche, Univ. of Washington (United States)
Miqin Zhang, Univ. of Washington (United States)

Published in SPIE Proceedings Vol. 4810:
Properties of Metal Nanostructures
Naomi J. Halas, Editor(s)

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