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Proceedings Paper

Three-dimensional imaging using TDI CCD sensors
Author(s): Aaron Fenster; David W. Holdsworth; Maria Drangova
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Paper Abstract

Atherosclerosis is an arterial disorder characterized by the development of arterial plaques which reduce the distensibility of the artery and obstruct blood flow. Little is known about the mechanisms which initiate the plaques and cause them to grow; however, it is generally agreed that hemodynamic factors are associated with the development of atherosclerosis. To study this disease it is essential to know not only the geometry of the arterial lumen but also the shape of the intimal surface in order to assess the importance of hemodynamic effects. The authors constructed a table-top volume CT scanner with high resolution in all 3 dimensions, which can be used to analyze human arterial specimens in vitro. This system uses an x-ray image intensifier optically coupled to a TDI CCD sensor to obtain low-noise, low-scatter projection digital radiographs from many angles. A slot beam of radiation is scanned across the sample to reduce the detection of scattered radiation without causing excess x-ray tube heating. Objects to be imaged are placed on a computer-controlled stage and projections are obtained as the specimen is rotated through 180 degree(s). CT reconstructions of the resulting data produces volume images with 0.12 X 0.12 X 0.15 mm3 volume resolution.

Paper Details

Date Published: 1 July 1991
PDF: 6 pages
Proc. SPIE 1447, Charge-Coupled Devices and Solid State Optical Sensors II, (1 July 1991); doi: 10.1117/12.45313
Show Author Affiliations
Aaron Fenster, John P. Robarts Research Institute (Canada)
David W. Holdsworth, John P. Robarts Research Institute (Canada)
Maria Drangova, John P. Robarts Research Institute (Canada)

Published in SPIE Proceedings Vol. 1447:
Charge-Coupled Devices and Solid State Optical Sensors II
Morley M. Blouke, Editor(s)

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