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Proceedings Paper

Design and characterization of a large-area lens-coupled CCD detector for macromolecular crystallography
Author(s): Edwin M. Westbrook; John Morse; Robert E. Fischer; William M. McGuigan; Steven K. Onishi; Paul Vu; Istvan Naday; C. Bauer; J. Phillips; T. A. Thorson; Roger D. Durst
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Paper Abstract

We have prototyped and characterized a very large format X-ray detector for macromolecular crystallography. The X-ray field strength is converted to visible light in a phosphor film. Light from the phosphor is focused onto a CCD imager by a lens specially designed for this detector, that has a very high numerical aperture. The CCD is very large (61 mm, 4,096 × 4,096 pixels), and employs a very low-noise on-chip preamplifier. Lens coupling between phosphor film and CCD avoids many of the optical imperfections of fiber optic coupling, but it remains a challenge to make a lens system with optical transfer efficiency matching or exceeding that of fiber optical systems. We have met this challenge by enhancing system gain in our detector through implementation of modern lens technologies and imaginative CCD design. At this point the system gain equals that of conventional CCD-based X-ray crystallography detectors, which couple the CCD to the phosphor through a fiber optic taper. Although many of our technical developments could also be used in fiber optic detectors, the overriding virtues of the lens-couple detector are simplicity, optical perfection, and cost.

Paper Details

Date Published: 10 January 2003
PDF: 11 pages
Proc. SPIE 4784, X-Ray and Gamma-Ray Detectors and Applications IV, (10 January 2003); doi: 10.1117/12.451165
Show Author Affiliations
Edwin M. Westbrook, Molecular Biology Consortium (United States)
John Morse, Molecular Biology Consortium (United States)
Robert E. Fischer, Optics 1, Inc. (United States)
William M. McGuigan, Optics 1, Inc. (United States)
Steven K. Onishi, Fairchild Imaging Inc. (United States)
Paul Vu, Fairchild Imaging Inc. (United States)
Istvan Naday, Argonne National Lab. (United States)
C. Bauer, Bruker-AXS Inc. (United States)
J. Phillips, Bruker-AXS Inc. (United States)
T. A. Thorson, Bruker-AXS Inc. (United States)
Roger D. Durst, Bruker-AXS Inc. (United States)

Published in SPIE Proceedings Vol. 4784:
X-Ray and Gamma-Ray Detectors and Applications IV
Ralph B. James; Edwin M. Westbrook; Roger D. Durst; Larry A. Franks; Arnold Burger; Edwin M. Westbrook; Roger D. Durst, Editor(s)

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