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Proceedings Paper

Algorithm using LSP to find symmetric axes of chromosomes
Author(s): Yang Wang
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Paper Abstract

Chromosomes are the primary objects studied in cytogenetics. Recent efforts have been devoted to automating the analysis of banded metaphase chromosomes. Feature extraction is the first step to identify a chromosome. Many useful features, such as the length and the number of bands of a chromosome, can be measured along with the chromosome's longitudinal symmetric axis. Therefore, finding this axis is a necessary precursor to making those measurements. In this paper, a new algorithm for finding a symmetric axis of a chromosome is discussed. The author introduced a concept of local symmetric property of an oblong object, and, then, applied this concept to a chromosome to find the symmetric axis after the boundary of the chromosome has been found. The results of the experiments show that the algorithm works well for both straight and bent chromosomes. Since the algorithms is based on the geometric properties of an object rather than its biological properties, it also can be used to find the symmetric axis of any other oblong object.

Paper Details

Date Published: 7 December 2001
PDF: 8 pages
Proc. SPIE 4472, Applications of Digital Image Processing XXIV, (7 December 2001); doi: 10.1117/12.449779
Show Author Affiliations
Yang Wang, Southwest Missouri State Univ. (United States)

Published in SPIE Proceedings Vol. 4472:
Applications of Digital Image Processing XXIV
Andrew G. Tescher, Editor(s)

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